"CLINICAL USES OF RARE DISEASES."

Professional clinical guidelines for rare diseases: methodology

Guidelines are systematically developed statements to assist practitioner and patient decisions about appropriate health care for specific clinical circumstances [1]. They concern often complex diagnostic or therapeutic strategies with several possible interventions at each step, where each intervention has to be assessed and compared with other possible interventions at short and long term for...

orofacial manifestations of neurological diseases

چکیده ندارد.

Clinical trials in rare diseases: a review of practice

Background The evaluation of treatments for rare diseases presents a number of challenges for trial practitioners, regulators and policy makers. Small sample sizes mean that ‘standard’ approaches to trial design and analysis may not be appropriate and alternatives such as Bayesian trial designs have been recommended [Lilford et al 1995]. However, little is known about the design and analysis ap...

Osteoblastoma of Mandible:A Rare Clinical Presentation

Clinical Uses of Probiotics

Probiotics are live nonpathogenic microorganisms. Many of these microorganisms are part of the normal human gut flora, where they live in a symbiotic relationship. Probiotics have been used to treat gastrointestinal (GI) and non-GI medical conditions. However, the data supporting their use are often conflicting, especially for non-GI-associated illnesses. The strongest evidence supporting the u...